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Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain

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This is important because it ensures your cells have the tools they need to stay resilient over the long term

Over 2000 years ago, the Egyptians and Romans already washed out their bowels to flush substances that supposedly caused disease

Indeed, measurements of noradrenaline (NA)-induced aerobic glycolysis by FRET nanosensors in individual astrocytes demonstrated an increased glucose utilisation, manifested as reduced NA-elevated free cytosolic glucose concentration, whereas the production of lactate by NA was unaltered