May relate to blood pressure effects
Differential targeting of GSH1 and GSH2 is achieved by multiple transcription initiation: implications for the compartmentation of glutathione biosynthesis in the Brassicaceae
The increase in MDHAR activity has been reported in stress conditions like salinity, high light, UV radiation, boron toxicity and low temperature (Mittova et al., 2003
Helps combat oxidative stress caused by lifestyle, stress, and inflammation
Conversely, patients who carry variants in hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13, rs72613567) and mitochondrial amidoxime-reducing component 1 (MARC1, rs2642438) are more protected than the general population (48, 49)
Modern lifestyles and environmental factors often create a demand for glutathione that exceeds what we can reasonably get from food sources.