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If left unmanaged, it can lead to: Bloating Gas Abdominal pain Hemorrhoids from straining Rectal discomfort or anal fissures And in rare cases, severe constipation can lead to impaction (where stool gets stuck in the colon and cant pass on its own)

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The dual GIP and GLP-1 receptor agonist mechanism requires adequate tirzepatide levels for maximum appetite suppression and metabolic benefits

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