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Samples were then precipitated with ice-cold MeOH, and supernatants were retained and evaporated overnight using a SpeedVac system at 37 C

Intracellular metal ions released from internalized metal-based NPs can depolarize the mitochondrial membrane and disturbance of electron-transport chain, eventually leading to mitochondrial dysfunction (Fu et al., 2014

Laboratory models indicate that it may support collagen and glycosaminoglycan synthesis, with observations pointing toward possible stimulation of fibrillogenesis

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There have been patients who have had severe nausea and diarrhea after its use

A similar line of reasoning involves the kidney in the manifestations of the high-folatelow-vitamin B-12 interaction: depletion of serum vitamin B-12 may also be the result of preferential uptake of folic acid into the renal proximal tubule cells via FR-