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NIH research review Found that KPV acts locally in the colon, minimizing systemic side effects seen in traditional IBD medications

Systemic effects remain less certain because peptides are generally broken down during digestion, which reduces the amount that reaches circulation in active form

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The peptide is one of two skin remodeling substances that may be able to downregulate the expression of metastatic genes.3 In a 1983 animal study (published in 2014) that was conducted in part by Dr