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354 Many age-associated dermatoses can develop or contribute to chronic skin disorders such as actinic keratosis (precancerous lesions), psoriasis, 355 prurigo nodularis, 356 and pigmentation issues such as senile lentigo and melasma

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CCK-8 assay was performed to assess the effects of metformin and simvastatin on cell proliferation after 24 h, 48 h, and 72 h of treatment

Mechanistically, TB-500s parent peptide (T4) drives endothelial cell migration, tubule formation, and angiogenesis, processes essential for granulation tissue and perfusion during healing