El gran problema de estos frmacos es que no diferencian entre grasa y msculo, lo que aumenta el riesgo de sarcopenia, es decir, fragilidad, prdida de masa muscular y peor calidad de vida, sobre todo en pacientes de edad avanzada (25)
Pharmaceutical companies have developed longer-acting versions of GLP1s, which have been shown to be effective in treating diabetes and obesity, but there is still a need for guidelines on the long-term use and potential tapering off of the medication 6m0s
4l, m and Supplementary Fig
Pregnant or breastfeeding women and individuals with specific health conditions should consult their doctor before starting
In ob/ob obese mice, a low iron diet or iron chelation therapy protected against -cell failure and insulin resistance and lowered triglycerides, but these effects were not replicated in healthy weight mice [38]