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Apart from other genes, glutathione S-transferase Mu class gene (GSTM1) from the human genome has been edited using CRISPR-Cas9 system (Sanjana et al., 2014)

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During dopamine (DA) metabolism, highly ROS are produced, placing dopaminergic neurons in a higher oxidative state compared to other neuronal populations (Sadaka et al., 2023)