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Early and smaller studies suggested effects on fat metabolism and body fat distribution, but larger obesity trials did not show a robust, clinically meaningful weight loss outcome on their own

Ferroptosis Ferroptosis is a non-apoptotic form of regulated cell necrosis driven by lipid peroxidation and dependent on iron regulation, closely related to iron overload and lipid peroxide generation [57]

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Physical exam : To identify any underlying issues like muscle loss or fatigue

Other participants discussed reduced anxiety levels secondary to better control of blood glucose and/or food intake