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Testicular Effects: Experimental data indicate GLP-1 receptor presence in Leydig and Sertoli cells

Gupte, R

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[DOI] [PubMed] [Google Scholar] (280).Wang D

In addition, the tricarboxylic acid cycle or electron transfer chain in the mitochondria can promote lipid ROS accumulation and is involved in cysteine-deprivation-induced ferroptosis [18]

An additional constraint could arise from the fact that while ferrostatin-1 has also previously shown efficacy in inhibiting ferroptosis in other human organoid models, such as bronchial [56] and gut crypt organoids [57], its utility is hindered by its solubility issues