1 Introduction Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are two naturally occurring hormonal peptides produced in gastrointestinal tract, knowns as incretins
GLP-1s (short for glucagon-like peptide-1 receptor agonists) work by helping regulate appetite, blood sugar, and metabolism
Phase 2 data showed 24.2% average weight loss at 48 weeks
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Maybe GLP-1 drugs seem to do everything because obesity (and high blood sugar) are broadly bad for you, and anything that reduces obesity (or high blood sugar) is broadly good for you
The mean systolic blood pressure reduction was 5.3 mm Hg for semaglutide, 6.5 mm Hg for tirzepatide 15 mg, and 3.6 mm Hg for tirzepatide 10 mg