doi: 10.1007/s00125-011-2232-3 188 WellenKEHotamisligilGS
A pooled analysis of over 11,000 patients showed an adverse event profile comparable to placebo (Tuthill et al., Ann N Y Acad Sci 2010)
For instance, in April 2023, Eli Lilly and Company notified that tirzepatide 10 mg and 15 mg demonstrated 15.7% weight loss in adults with obesity and type 2 diabetes in 72 weeks, resulting from SURMOUNT-2 clinical trials
Patients should work closely with their healthcare team to ensure weight loss occurs at a sustainable rate, ideally around 0.5-1 kg per week where possible
Low stomach acid Individuals with conditions that equate to lower acid production in the stomach are prone to B12 deficiency, as acid is essential to the absorption process
The glycocalyx and its significance in human medicine