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Today, were talking about how the rapid rise in the use of GLP-1 marks a shift in the treatment landscape for obesity care and why nutrition is central to supporting patients on weight-loss medications

There are a few treatments still in the experimental phase which hold future promise for the therapy of HE (Table 3) such as Minocycline, which reduces microglial cell activation in cerebral insult and results in a reduction of brain edema as well as plasma and CSF ammonia levels

This has led to a focus on signaling pathways and neuroendocrine mechanisms to develop targeted obesity treatments

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