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There is a widespread and popular belief regarding reactive astrogliosis and astrocytic perilesional border as a harmful reaction that limits regenerative capacity of the nervous tissue

For most oral supplements, 2,000 mg per day is considered the upper safe limit for short-term use

Ethical approval and informed consent Not applicable

It may lead to physical or psychological dependence, or what we can call opioid addiction

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The intertwined dysregulation of copper and iron metabolism further exacerbates the disease by promoting apoptosis in lipid-rich foam cells and VSMCs, which are particularly vulnerable to metal-dependent cell death [195, 196]