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Genome wide transcriptome analysis revealed that the Hippo-effector YAP, which is associated with immature cardiomyocyte proliferation, was upregulated in the cardiomyocytes of -blocker treated and Gnas cardiac-specific knockout hearts

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PubMed Slominsky, P.A., Shadrina, M.I., Kolomin, T.A., et al

The primary end-point was defined as 1-point reduction in the WHS of HE over 4 weeks