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doi: 10.1056/NEJMoa1901118 84 McGuireDKBusuiRPDeanfieldJInzucchiSEMannJFEMarxNet al

A: PPS will need to provide updates on milestone progress and workforce process measures for quarterly progress reports

Firstly, these medications slow down the rate at which food empties from the stomach into the small intestine

As a result, endocrine responses remain largely confined to growth hormone pathways in controlled experimental models

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instead, it reduces calorie intake by suppressing appetite, creating a calorie deficit through behavioral and physiological appetite suppression rather than metabolic acceleration