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Retatrutide , developed by Eli Lilly, is a novel triple agonist that simultaneously activates three receptors: GLP-1 (glucagon-like peptide-1) receptor reduces appetite and slows gastric emptying GIP (glucose-dependent insulinotropic polypeptide) receptor enhances insulin secretion

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Its importance lies in its ability to replenish and boost the bodys glutathione stores

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As a cell protective antioxidant, amifostine acts by scavenging free radicals, supplying hydrogen ions to free radicals, depleting oxygen, accelerating DNA repair and suppressing Fas/FasL-mediated apoptosis [146]