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Pernicious anemia is an autoimmune disease characterized by the absence of intrinsic factor, a glycoprotein that is necessary for vitamin B 12 absorption [25, 26]

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When to Consider Oral Vitamin B12 Supplements For Maintenance or Mild Deficiency : If youre generally healthy and need B12 supplementation to maintain healthy levels or correct a mild deficiency, oral supplements are a convenient and cost-effective option

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doi: 10.1371/journal.pone.0044307 52 BrustelJMuramotoTFumimotoKEllinsJPearsCJLakinND