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labile iron pool) are present at very low concentrations due to the metal sequestration

A systematic review looking at the emerging evidence on the association between IrAEs and clinical outcomes highlighted the existence of a plausible direct proportionality of a therapeutic effect across ICI agents and solid tumours [47]

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ADA1 can form a 280kDa complex with a dimer of DPP4 or ADBP or adenosine deaminase complexing protein (ADCP)