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NF-B has been described as a master regulator of inflammation since it regulates the expression of multiple inflammatory genes

Oktay K, Harvey BE, Partridge AH, Quinn GP, Reinecke J, Taylor HS, et al

ZagrodzkiP.BartonH.WalasS.FoltaM.StomporT.Janusz-GrzybowskaE.DrozdzM.SulowiczW.2007Selenium status indices, laboratory data, and selected biochemical parameters in end-stage renal disease patients.1162941

However, its future trajectory in clinical medicine hinges on overcoming significant hurdles and navigating a complex scientific and regulatory landscape

Y., & Jorgensen, J

Activation of YAP can induce the expression of SLC7A11, thereby enhancing cystine uptake by System XC-, increasing GSH level, thereby increasing GPX4 synthesis, thus reducing ROS level and inhibiting ferroptosis [16, 17]