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The mechanism involves glycine exerting a hyperpolarizing effect on macrophages and other immune cells, inhibiting calcium influx through voltage-sensitive channels and thereby dampening their inflammatory activity

Meyerhoff O, Mller K, Roelfsema MRG, Latz A, Lacombe B, Hedrich R, Dietrich P, Becker D (2005) AtGLR3.4 , a glutamate receptor channel-like gene, is sensitive to touch and cold