ROS exert cellular toxicity by modifying DNA, lipids, and proteins through DNA base oxidation, lipid peroxidation, and protein carbonylation (protein oxidation), respectively 79
As understanding of ferroptosis mechanisms deepens and multidisciplinary innovations progress, a multifaceted approach to targeting ferroptosis may ultimately emerge as a breakthrough for OA management by delaying disease progression and enhancing patients quality of life
Clinically, B12 shots have long been used to treat cyanide poisoning
Vitamin B12 is a vital nutrient that plays a key role in the production of red blood cells, maintaining healthy nerve function, and supporting DNA synthesis
Putting cancer to sleep at night: the neuroendocrine/circadian melatonin signal
This L-Glutathione antioxidant peptide participates in oxidative stress regulation, enzymatic detoxification pathways, redox homeostasis, and cellular protection mechanisms