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Tirzepatide has a long half-life (about 5 days ), and it may take 46 weeks to be fully cleared from the body

Nat Rev Nephrol 3 , 397404 (2007)

When you start semaglutide, your gastrointestinal system becomes more sensitive to food composition and meal size

Best Pract Res Clin Endocrinol Metab 34(1):101388 Antonelli A, Ferrari SM, Corrado A, Di Domenicantonio A, Fallahi P (2015) Autoimmune thyroid disorders

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Time-restricted eating to prevent and manage chronic metabolic diseases