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In the small published human studies to date, BPC-157 was well tolerated, with no meaningful changes in cardiac, hepatic, renal, or metabolic markers

Key principles often include: Holding weight stable before dose reductions Avoiding simultaneous aggressive calorie restriction Maintaining protein intake and resistance training Supporting metabolic health during transition The goal is not continued weight loss during tapering it is durable stability

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The effect of GLP-1 on fod intake is lost in Truncal vagotomized subjects