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Further, a previous study, found that CR reduces both A and tau accumulation and improved cognitive performance in the 3xTg mouse model of AD 4

Coronal sections in the hippocampus of control, GbE, and LC groups (Fig

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Almazan et al., [83] indicated that the intrahippocampal administration of a TNFR2-specific blocking antibody improved recognition memory, spatial memory, and synaptic potentiation in response to chemically induced LTP (cLTP) in 5xFAD mice