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In a subsequent study, lean Gipr AP-KO and Gipr AP-GFP mice were switched to an HFD on the same day as initiating 10 days of daily injections with either LIRA (or VEH) alone, or LIRA (or VEH) plus GIPR antagonist peptide (GIPR-antag) 6

Final Thoughts on SS-31 Peptide Therapy in 2026 SS-31 occupies a unique position in the peptide landscape: it is the only available compound that specifically targets the inner mitochondrial membrane, addressing cellular energy production and oxidative stress at the most fundamental cellular level

It was developed by Theratechnologies in Montreal and received FDA approval in 2010 based on two large Phase 3 trials showing 15% visceral fat reduction

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Liu P, Tong Z, Zheng Y, Li Q, Liang Q, Qi Q (2021) Screening and genome analysis of a Pseudomonas stutzeri that degrades PET monomer terephthalate

The two peptides are studied for tissue repair through different mechanisms