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Since efficacy holds across the menopausal transition, the choice between Peak and Ro comes down to cost and access, not whether the drug will work

Immunology 151(4):363374 Jensen AB, Srensen TI, Pedersen O, Jess T, Brunak S, Allin KH (2018) Increase in clinically recorded type 2 diabetes after colectomy

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Fundamentally, GLP-1RAs work by stimulating insulin secretion and inhibiting glucagon secretion in a glucose-dependent manner [9], which explains their associated low risk of hypoglycaemia