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However, autophagosome markers are decreased which may indicate there was a defect in the removal of mitochondria fragments, while reduced mitophagy markers may indicate that there were less healthy mitochondria fragments to be recycled

Water (Fluid) Retention: Causes, Symptoms, Treatment for Edema Water retention, called edema, refers to excess fluid that is improperly stored in the muscles and other organs of the body

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Reference Pizzorno J