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doi: 10.2337/dci18-0033 39 McGillJBSubramanianS

Elevated ROS reinforce TGF-/Smad signaling, driving hepatic stellate cell transdifferentiation into myofibroblasts and fibrogenesis [414]

[DOI] [PMC free article] [PubMed] [Google Scholar] 98.Cantando I., Centofanti C., DAlessandro B., Limatola C., Bezzi P

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Semaglutide dose-dependently reduced liver enzymes, and resulted in greater NASH resolution (reduced ballooning and lobular inflammation) without worsening of fibrosis, as compared with placebo after 72 weeks of treatment

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