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Another study (45) in male PD rats showed that electroacupuncture at the same acupoint set (Taichong, Fengfu, and Zusanli) elevated mRNA expression of PINK1, Parkin, Beclin-1, and LC3 while reducing expression of -syn and p62

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Typical descriptions of this symptom include a patient who goes to bed and awakens by severe pain in the big toe but may also be experienced in the heel, instep or ankle