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Results Selection of residues and generation of Grx mutants As reviewed recently 3 , structural studies on glutaredoxins revealed several residues that are involved in glutathione interactions (Fig

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Does vitamin E mitigate cisplatin-induced nephrotoxicity in cancer patients: results from a randomized placebo-controlled clinical trial

To test this hypothesis, we constructed the gpoA Cys36Ala mutant, which demonstrated a higher susceptibility to H 2 O 2 in reference to the wt strain, a similar phenotype displayed by the gpoA mutant (Fig 3B, Fig S2)

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M., & Wilson, S