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He doesnt doubt that the cases are real

3952 Elsevier

This raises an important question about long-term use that does not have a clean answer yet

10.1158/0008-5472.Can-07-1905 Cancer Res

It just may be that there are still unappreciated benefits to the old drug, metformin

That makes the contribution of GHK-Cu specifically to any reported endpoint difficult to attribute, and is one of the reasons independent reviewers do not regard the human evidence base as conclusive