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May work less well if theres psychosis present

Because it does not serve as a true weight-loss agent, its utility lies in its specificity

How GLP-1 Medications Compare The honest comparison is this: GLP-1 medications produce significantly greater average weight loss than bupropion-based options, they work through a different and more direct mechanism of appetite suppression, and they have additional metabolic benefits including improvements in blood sugar, blood pressure, and cardiovascular risk that bupropion doesnt offer

The disconnect between short plasma half-life and prolonged therapeutic effects observed in many studies supports tissue-level mechanisms extending beyond circulating peptide concentrations

There are no restrictions on physical activity post-injection

Too much cardio and not enough strength training or recovery: Overdoing high-intensity exercise without building muscle can actually worsen insulin sensitivity and fatigue