These are not marginal improvements
The ongoing dedicated ophthalmic trial named as FOCUS study, which aims to evaluate semaglutides long-term effects on diabetic retinopathy, is now ongoing and could contribute to a comprehensive understanding of the true risk-benefit profile of these agents in patients with or at risk for diabetic retinopathy (NCT03811561) [104]
Risk of Anaphylaxis Among New Users of GLP-1 Receptor Agonists: A Cohort Study
This may be of benefit for anyone with MCAS, and clinical trials are looking at the effectiveness of different doses.[ref][ref] Dementia prevention: Studies using data from diabetes patients showed a significant decrease in dementia for those on GLP-1s vs other diabetes medications
Most patients regain a substantial portion of lost weight within one year of discontinuing GLP-1 therapy, as appetite and metabolic parameters return toward baseline
Berberine can cause digestive issues like diarrhoea, constipation, excess gas, and an upset stomach