Activation of BECs by increasing the level of adhesion molecules has been shown to play a role in the recruitment of leukocytes to the CNS (Sweeney et al
To test if MS4A15 extensively inhibits ferroptosis, we generated pooled Ms4a15 -overexpressing mouse immortalized fibroblasts ( Ms4a15 OE) [32, 33] and characterized resistance to different ferroptosis inducers (1S,3R)-RSL3 (RSL3), imidazole ketone erastin (IKE), ferroptosis inducer derived from CIL56 (FIN56), and genetic ablation of Gpx4 (Fig
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B7-H3 mediates the immunosuppression via CCL2-CCR2 axis, which leads to M2 macrophage migration and differentiation as observed in ovarian cancer (88)
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M., Greten, F