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oxidized cardiolipin not only triggers NLRP3 but also signals for mitophagy (mitochondrial autophagy) as a quality control

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This surge strained state and employer budgets, leading many to restrict coverage to control costs

Side effects are rare but may include mild redness, swelling, or soreness at the injection site

Furthermore, since CHE is an early sign of decompensation, the hazard ratio for mortality in patients with CHE is two to four times higher in affected patients [23, 24]