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The contribution of individual variables to the separation of clusters was assessed using Variable Importance Projection (VIP), with only those metabolites exhibiting VIP values greater than 1.3 being significant [35, 36]

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Stevens LE, Peluffo G, Qiu X, Temko D, Fassl A, Li Z, et al

doi: 10.1016/S1472-6483(10)60312-4 218 TremellenKMiariGFroilandDThompsonJ

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