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Senolytic drugs such as the BCL2 family inhibitors ABT-263 and ABT-737 23,24,34 selectively killed senescent IMR90 ER:RAS cells when compared with non-senescent controls (Extended Data Fig

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75 Conversely, overexpression of AHCY can rescue cell function by activating the Nrf2-HO-1 signaling pathway

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T-lymphocytes up-regulate the synthesis of ACh in the blood when activated [162]

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