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Furthermore, in the I/R model, cAMP stimulation is able to reduce the severity of kidney damage, reduce the accumulation of neutrophils and reduce the production of TNF- (Mizutani et al., 2005)

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The current repertoire of drugs aimed at glutamine metabolism can be broadly categorized into three classes, specifically glutamine antimetabolites, glutamine catabolic-related enzymes inhibitors, and glutamine uptake inhibitors [181]

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Interestingly, we found that increased VGF expression was accompanied by increased glucagon secretion (Supplementary Fig