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Real-world use of semaglutide for weight management: patient characteristics and dose titration: a Danish cohort study

Commercially available therapeutic lapidated GLP-1 analogues, semaglutide and liraglutide, have the significant advantage of prolonged in vivo half-lives (hours to days) compared to native GLP-1, which degrades within minutes

Early recognition of medication-induced gastroparesis is essential, as prompt discontinuation of the offending agent can lead to rapid symptom resolution and prevent serious complications such as acute kidney injury

Finding the right balance within the population of dual or triple agonists in development is going to be one of the toughest challenges

The completed studies measured safety and efficacy across key biomarkers related to appetite regulation, metabolic function, and nutrient absorption

Diabetes & Metabolic Syndrome: Clinical Research & Reviews 19 , 103212 (2025).