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A particular relationship was established with the NO-system, and the advantage of the BPC 157 over the corresponding standard agents (i.e., corticosteroids, sulfasalazine, H2 blockers, anticholinergics, and proton pump inhibitors) which showed only weak, if any, effect on these fistulas closing (Skorjanec et al., 2009

If its production is inhibited or limited, as it is with several types of genetic glitches then dysfunction and disease result