Retatrutide (12 mg weekly), TRIUMPH-4, 68 weeks: mean weight loss 28.7%
The compounds classification as a triple receptor agonist targeting GLP-1, GIP and glucagon receptors puts it at the forefront of metabolic research, giving scientists a way to study energy balance and glucose metabolism
Some patients notice initial improvements within one week, with optimal results developing around three months as collagen production increases
But not everyone with hereditary pancreatitis will have an identifiable genetic cause, and variations in other genes that havent been identified yet could also be responsible
The incretin effect is reduced in people with T2DM, mainly because GIP has less of an impact [85]
What Wegovy is Wegovy is a GLP-1 receptor agonist produced by Novo Nordisk