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(2017) 6:e383

Current Medicinal Chemistry , 19 (1), 126132

The figure below shows the mechanism of NAPQI generation and its further metabolism, as well as the possible mechanism of NAC in removing NAPQI

Elecoglipron is an oral small molecule GLP-1 RA (receptor agonist), Vanita Aroda, MD, director of Diabetes Clinical Research at Brigham and Womens Hospital, associate professor of medicine at Harvard Medical School, and lead author of this study, told Medical News Today