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Because GLP-1 therapy tackles underlying biological factors contributing to weight gain, it offers a more sustainable solution than traditional weight loss methods

Conversely, a target-trial emulation found small and variable cardiovascular differences between the two agents, though both outperformed non-incretin therapies (16)

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For athletes whose supplement schedules are already complex, having a fat burner that requires no scheduling adjustments or interaction management is a practical compliance advantage

Insulin resistance at baseline also plays a rolepatients with higher starting insulin levels often see faster initial results because semaglutide rapidly improves insulin sensitivity