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have reported that metformin combined with probiotic-derived outer membrane vesicles can modulate the gut microbiota and eliminate excess reactive oxygen species (ROS) in a murine inflammatory bowel disease (IBD) model [18]

Disc herniation involves both mechanical factors (the displaced disc material) and biochemical factors (inflammation)

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Thus, GSH participates in cysteine-induced signaling via its degradation and ability to replenish cysteine pool in HepG2 cells