Common Long-Term Side Effects and How to Manage Them Nausea remains the most frequently reported side effect during the first weeks of GLP-1 therapy, affecting 2540% of users in trials
Continue the small meals approach
Skyrocketing numbers of American adults are taking weight loss drugs like semaglutide (Wegovy, Ozempic)
In patients with type 2 diabetes, IGF-I level was in a normal range
Since patients with HF with New York Heart Association class IV were excluded from the CVOTs, it is unclear whether safety risks could occur in semaglutide-treated patients
In the same study, weight loss statistics showed reductions of 13.7% and 3.2% from baseline, with an estimated 10.5% greater weight loss with semaglutide. Some of the news isnt surprising: Obesity is a major risk factor for knee OA, and since semaglutide promotes weight loss by regulating appetite and blood sugar levels, its potential to reduce pressure on your knee joints is fairly well understood