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Crohns disease, celiac disease, bacterial overgrowth, and other GI conditions that affect this area of the gut can impair B12 absorption

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Genetic influences Once absorbed, glucosinolate-derived isothiocyanates (like sulforaphane) are promptly conjugated to glutathione by a class of phase II detoxification enzymes known as glutathione S -transferases (GSTs) ( Figure 3 )

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10.1152/jappl.1999.87.1.438 J Appl Physiol