The compound has gained so much attention that Wikipedia now has a section devoted to its social media popularity
Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line
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As an electrophilic chemical, ITCs might react covalently with the thiol groups of (proteins and) glutathione in plants, similar to what has been demonstrated in different in vitro systems 38,77,78 as well as in insects feeding on GSL or ITC diets 79,80
Microarray and RNA-sequencing studies have mapped its regulatory effect across approximately 4,000 human genes, including upregulation of VEGF, BDNF, and BMP-2 growth factors central to vascular, neural, and bone remodeling respectively
Free radicals in biology and medicine