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SFAs are also thought to directly induce an inflammatory response in the brain by activating toll-like receptor (TLR) receptors in microglia, causing elevated cytokines IL-6, interleukin-1 (IL-1), and TNF-, particularly in the hippocampus, which has been shown to correlate with depressive behavior in mice (3234)

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At the same time, it also assists in clearing out microbes from the upper intestinal tract.With a low-functioning or removed gallbladder, eating high-fat meals can cause many uncomfortable symptoms: Indigestion Nausea Bloating Heaviness in your right side Right shoulder pain And more Ox Bile provides 125 mg of pure bile from free-range oxen (bovine)

This suggests a modulatory role similar to the bidirectional regulation observed with the NO system