Future studies specifically designed to evaluate hormonal contributions (e.g., estrogenGLP-1 receptor interactions) will be important to mechanistically clarify these sex differences
Brand-name equivalent: Mounjaro / Zepbound Tirzepatide targets two metabolic pathways for enhanced appetite control and metabolic support
The ability of Semaglutide GLP-1, Mounjaro, Wegovy, and Ozempic to maintain long-term weight loss varies due to a number of individual circumstances
The authors would like to acknowledge helpful discussions with Guo Yang, Savitha Ramasamy, and Zhou Weizhuang, and support on compliance and governance from Nurensah Beevi at the Institute for Infocomm Research, A*STAR
Dipeptidyl peptidase 4 inhibitor sitagliptin protects endothelial function in hypertension through a glucagon-like peptide 1-dependent mechanism
MEDVi highlights that 93% of its patients keep the weight off after initial loss, provided they remain consistent with treatment and follow the care plan